Breached Barrier: Researchers have developed a drug delivery system that can surmount the blood-brain barrier, the toughest wall of defense in the body:
First the team coats the liposomes with a polymer called polyethylene glycol (PEG), without which they would be purged from the blood within minutes. Next, antibodies that latch on to some of the brain-capillary receptors are tehtered to a few of the PEG strands. The antibodies trick the receptors into letting the liposomes pass, where they can deliver their cargo to brain cells.
They think they might even be able to use this to deliver gene therapy to neurons. I don’t know if I’d want someone to mess around with the genes inside my head, but I suppose if I were terminally demented, it might be worth a shot. (But then, how would I give my consent?)
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